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How to deal with diabetic nephropathy? How to treat?
Diabetic nephropathy is a chronic complication of diabetes mellitus. Diabetic nephropathy is generally referred to as diabetic glomerulosclerosis, early symptoms of diabetic nephropathy is generally found in urine albumin. Gradually increased, the clinical manifestations of proteinuria, edema, hypertension or hyperlipidemia, and increased fasting blood glucose or diabetes symptoms. When diabetic nephropathy has obvious symptoms, many have entered the late stage, with the development of the course of disease, the clinical manifestations are also different.
This is the first sign of diabetic nephropathy. The glomerular filtration rate begins to decline after persistent proteinuria. With the development of the disease, the amount of urinary protein increased gradually, and the urinary protein content was consistent with the severity of renal lesion. When the glomerular filtration rate is significantly lower than normal, a large number of proteinuria, can quickly develop into renal failure. Such as 24 hours urine protein less than 3 grams, the amount of urinary protein was not significantly increased, the progress of renal failure slow.
There are approximately half of the patients appeared edema and edema in nephrotic syndrome, may be caused by hypoproteinemia caused by loss of a large amount of protein in the urine, but older, caused by other causes of edema is more also, about 20% of the patients with nephrotic syndrome.
This is a relatively advanced symptoms of hypertension, appear in patients with a longer period of proteinuria. The initial increase in blood pressure after the exercise, there is a persistent proteinuria, blood pressure continued to increase, the emergence of high blood pressure accelerated the deterioration of renal function in patients with diabetic nephropathy.
Renal failure early in order to meet the needs of the row of sugar, increased glomerular filtration rate, blood urea nitrogen and creatinine levels in normal, persistent proteinuria, blood urea nitrogen and creatinine concentration, renal insufficiency, within a few years may progress to end-stage renal failure.
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