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Tongshantang expert:diabetic nephropathy causes of edema

Edema for the organization of excess fluid effusion of a pathological phenomenon, especially in the lower limb edema is the most common. Diabetic patients with lower extremity edema, in addition to a few reasons, most of the chronic complications associated with diabetes, is a sign of many chronic complications. Common in the following cases:

Diabetes complicated with renal insufficiency

Diabetic nephropathy is the most common cause of lower extremity edema in diabetic patients. Diabetic patients with renal damage, due to a large number of urine protein leakage, decreased ball filtration rate and severe hypoproteinemia caused by both lower extremities, eyelids and facial swelling, severe systemic edema may occur. Patients with urine routine examination can be seen protein and tube, renal function indicators (such as creatinine, urea nitrogen) increased can be identified.

Diabetes complicated with heart disease

Diabetes is easy to complicated by coronary heart disease, cardiomyopathy and other cardiovascular diseases, severe illness may be due to cardiac dysfunction (especially right ventricular dysfunction) caused by systemic congestion and sodium and sodium retention, leading to jugular vein engorgement, hepatosplenomegaly and double Symptomatic edema of lower extremities. This patient is often accompanied by palpitation, chest tightness, shortness of breath and other cardiovascular symptoms and ECG ischemic changes can be identified.

Diabetes complicated with peripheral neuropathy

Diabetic neuropathies more common in the lower limbs, and the position, activities related. This is due to plant nerves (mainly sympathetic) damage, causing peripheral blood vessels to expand congestion, both lower extremity venous congestion and edema; In addition, neurotrophic disorders caused by increased local capillary permeability, can also cause lower extremity edema. Diabetic neuropathy caused by edema, mostly accompanied by acral numbness, pain, socks like sensory loss and other symptoms, can be identified.

Diabetes combined with lower extremity vascular lesions

When the patient's lower extremity venous lesions (such as deep vein thrombosis, venous valve insufficiency), leading to venous return obstruction caused by intravenous pressure, there may be lower extremity edema, but often unilateral edema.

Diabetes with foot infection

Patients with foot skin damage, local inflammatory response can also lead to edema, such patients are often accompanied by local skin temperature, skin redness, pain and other acute inflammatory performance.

Diabetes complicated with severe malnutrition

Some patients with diabetes, due to long-term diet, calories and protein intake is seriously inadequate, leading to hypoproteinemia and malnutrition edema.

Drug factor

Some hypoglycemic drugs and antihypertensive drugs can cause water and sodium retention, resulting in lower extremity edema. The former such as insulin, thiazolidinediones (such as rosiglitazone, pyrrolidone); the latter such as calcium antagonists (such as nifedipine, amlodipine). The common feature is that edema occurs after the drug, shortly after the withdrawal disappears.

Diabetes combined with hypothyroidism

Some patients with diabetes (especially in elderly women) at the same time combined with hypothyroidism, which can cause lower extremity or facial mucus edema, which is characterized by finger press the edema site does not appear depression changes. In addition, hypothyroidism patients often have fatigue, lethargy, cold, bradycardia, constipation and other symptoms associated with the test showed thyroid function (FT3, FT4) can be identified low.

Idiopathic edema

Female diabetic patients with lower extremity edema, we should pay attention to exclude "idiopathic edema." This swelling often occurs in the reproductive age, patients often accompanied by neurosis symptoms, edema is often associated with the menstrual cycle. "Lying down water test" positive will contribute to the diagnosis of idiopathic edema edema.

other

Diabetic patients such as chronic liver disease, etc., may also occur lower extremity edema. Patients with chronic liver disease (such as poor tolerance, liver disease face, liver palm, spider nevus, jaundice, etc.) and liver dysfunction, combined with liver and gallbladder B ultrasound examination can be identified. In short, the causes of diabetes edema is multifaceted, to the patient's specific circumstances, specific analysis, in order to find out the reasons, and to give targeted treatment.

diabetic nephropathy causes of edema
diabetic nephropathy causes of edema

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