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What Is Renal Hypertension?|Renal Hypertension: Symptoms, Ca
The kidney is both an important organ of blood pressure regulation and is one of the major target organs of hypertension. The kidneys are responsible for the regulation of blood volume, electrolyte balance, and regulation of renin-angiotensin system (RAS). Kidney is rich in blood vessels, vulnerable to high blood pressure damage. Normal renal function plays an important role in maintaining blood pressure stability. Once the damage to renal function, will increase the high blood pressure, hypertension and further increase kidney damage, so the formation of a vicious cycle, leading to renal insufficiency and heart, brain and other vital organs damage.
Clinically caused by changes in renal structure and function of hypertension, known as hypertensive renal damage, mainly small arterial renal sclerosis. Hypertension for 5 to 10 years, can cause renal small arteriosclerosis (arcuate and interlobular artery intimal thickening, small arterial hyaline), wall thickening, lumen narrowing, and then Renal parenchymal ischemic damage, including glomerular ischemic shrinkage, sclerosis, tubular atrophy, renal interstitial cell infiltration and fibrosis, leading to benign arterial nephrosclerosis; and rapid hypertension or malignant Hypertension caused by malignant small arterial nephrosclerosis is currently relatively less.
In recent years, due to the increasing number of patients with hypertensive, the incidence of benign small arterial nephrosclerosis is also significantly increased. The disease is more common in Western countries, is the end stage of renal failure, the second cause (about 25%), only second to diabetic nephropathy. In our country, benign small arterial nephrosclerosis in the end stage renal failure peritoneal dialysis and hemodialysis patients, accounted for second (14.8%) and the third place (8.9%), in the peritoneal dialysis only second to chronic Nephritis, only second to chronic nephritis and diabetic nephropathy in hemodialysis. However, the harm of high blood pressure to the kidney has not been fully understood.
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