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Do you know about infant polycystic kidney heredity?

What is the genetic regular of human polycystic kidney?

Autosomal dominant polycystic kidney disease (ADPKD) is an adult polycystic kidney disease that follows an autosomal dominant inheritance that is:

1, the same incidence of men and women;

2, one of father or mother has sick, the incidence of children less than 50%, if parents both are sick, the incidence of children increased to 75%;

3, non-sick children do not carry cyst gene, and no heterosexual marriage with the disease, their children (grandchildren) will not be disease, that is not intergenerational heredity.

what is the genetic regular of infant polycystic kidney?

An autosomal recessive polycystic kidney disease (ARPKD), an infantile polycystic kidney disease, has the potential for the onset of the child's disease when both parents carry the gene for the disease, with a 25% chance of developing and a gene transfer of 50%. But parents themselves generally do not get sick, this is the meaning of recessive inheritance. Patients often die within a few hours or days after birth, light can live to several years, or even adults. The patient's kidneys increased significantly, for the normal 10 times, there are many radiologically arranged, relatively uniform size of the prismatic cysts (mainly made by the expansion of the collection tube). Most cases of illness also have liver disease (fibrosis and portal hypertension, etc.). Liver, kidney lesions often inversely proportional. Finally died of renal failure or liver complications.

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Do you know about infant polycystic kidney heredity?

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