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What are the typical symptoms of chronic renal insufficiency
The first stage of renal insufficiency: renal insufficiency compensatory period, serum creatinine (Scr) 133 ~ 177umol / L, because of renal compensatory ability, therefore clinical renal function was decreased, but the excretion of metabolites and regulate the balance of water and electrolyte can still meet the normal requests, the symptoms are not clinically, kidney function tests in the normal range or occasionally slightly high phenomenon.
The second stage of renal insufficiency: renal insufficiency decompensated (also known as renal insufficiency azotemia), serum creatinine (Scr) 177 ~ 443umol / L, the number of glomerular sclerosis fibrosis increases, about 60%-75% damage, kidney excretion metabolism waste has certain obstacles, blood creatinine, urea nitrogen is high or above normal. Patients with anemia, fatigue, weakness, weight loss, the spirit is not easy to focus, but often overlooked. If there is water loss, infection, bleeding, etc., the disease progression will accelerate.
The third stage of renal insufficiency: renal failure, serum creatinine (Scr) 443-707umol / L, glomerular sclerosis, renal tubular - interstitial fibrosis, renal vascular fibrosis, leading to severe renal dysfunction, anemia, Nocturia increased, serum creatinine, blood urea nitrogen increased significantly, and often acidosis, this period without the system of regular treatment, will develop to end-stage renal disease, treatment more difficult.
The fourth stage of renal insufficiency: uremic or end stage of renal insufficiency , serum creatinine (Scr) "707umoll / L. Renal insufficiency in uremic patients is more than 95% of glomerular lesions, severe clinical symptoms, such as severe nausea, vomiting, oliguria, edema, malignant hypertension, severe anemia, skin itching, mouth urine smell and so on.
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