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Blood purification is a therapy which helps remove the waste products in the body by filtering the blood. Dialysis is a very common branch of blood purification. However, dialysis only deals with the small sized toxins in the blood. If you are in kidney failure, the medium and larger waste products should be removed by other techniques of blood purification.
Currently, blood purification includes hemodialysis, hemofiltration, hemoperfusion, immune adsorption, plasma exchange,CRRT. Here are some basic information for your reference.
Hemodialysis is a technique which is used to remove the small sized waste products in the blood, such as creatinine, urea and extra water. Hemodialysis is the most common way to treat advanced, permanent kidney failure. The procedure can help you carry on an active life despite failing kidneys. Hemodialysis is a serious responsibility, but you don't have to shoulder it alone. You'll work closely with your health care team, which will include a kidney specialist and other professionals with experience managing hemodialys
Compared with hemodialysis, hemofiltration is always used in intensive care settings in case of acute renal failure. And it removes both the small and middle sized wastes in the blood, such as chemicals, bilirubin and excessive vitamins.
Hemofiltration has the advantage of removing solutes small enough to pass through the ultrafilter in proportion to their plasma concentration rather than their concentration gradient, as with diffusion.The driving force is a pressure gradient rather than a concentration gradient. The rate of solute removal is proportional to the applied pressure that can be adjusted to meet the needs of the clinical situation.
Hemoperfusion is a treatment technique in which large volumes of the patient's blood are passed over an adsorbent substance in order to remove toxic substances from the blood. It deals with all the small and middle sized toxins, as well as a few large sized wastes in the blood.
Hemoperfusion is sometimes described as an extracorporeal form of treatment because the blood is pumped through a device outside the patient's body.
Immune adsorption is a therapy which uses adsorbing materials to alternatively or specifically remove the pathogenic factors related to immune system in the blood. It usually used in immune system diseases and liver diseases.
Immune adsorption takes DNA antigen as aglucon to combine with spherical carbonization resin carrier and form the adsorbent, whose special adsorptive function will be applied to clean the pathological factors such as immune complex in Renal Failure patients' blood selectively and specially.
Plasmapheresis is done to exchange plasma in the blood. Plasma is the liquid part of the blood that does not contain cells. Once the plasma is removed, fresh plasma or a plasma substitute is added back to the blood.
It shows promising effects in treating the following kidney diseases: anti-glomerular basement membrane disease, Acute Glomerulonephritis, serious Focal Segmental Glomerulonephritis, Lupus Nephritis, crescent Glomerulonephritis, immune kidney disease, lipoprotein glomerulopathy etc.
CRRT, Continuous Renal Replacement Therapy as its full name, is designed to provide artificial kidney support to patients who could not tolerate traditional hemodialysis. CRRT is intended to run for 24 hours a day, but the average therapy time is actually closer to 16 hours a day due to interruption. It deals with all sized waste molecules in the blood.
If your patient is critically ill with acute kidney injury (AKI), CRRT is one of the primary therapies. The goal of any continuous renal replacement therapy (CRRT) is to replace, as best as possible, the lost function of kidneys. CRRT provides slow and balanced fluid removal that even unstable patients - those with shock or severe fluid overload - can more easily tolerate. Both average and smaller size patients can undergo CRRT therapy and it can be adapted quickly to meet changing needs.